Articles | Volume 7, issue 5
https://doi.org/10.5194/jbji-7-213-2022
https://doi.org/10.5194/jbji-7-213-2022
Original full-length article
 | 
20 Oct 2022
Original full-length article |  | 20 Oct 2022

Utility of disc space aspirate cell counts and differentials in the diagnosis of native vertebral osteomyelitis

Talha Riaz, Matthew Howard, Felix Diehn, Aaron Joseph Tande, Courtney Ross, Paul Huddleston, and Elie Berbari

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Cited articles

Babic, M. and Simpfendorfer, C. S.: Infections of the Spine, Infect. Dis. Clin. North Am., 31, 279–297, https://doi.org/10.1016/j.idc.2017.01.003, 2017. 
Berbari, E. F., Kanj, S. S., Kowalski, T. J., Darouiche, R. O., Widmer, A. F., Schmitt, S. K., Hendershot, E. F., Holtom, P. D., Huddleston III, P. M., Petermann, G. W., and Osmon, D. R.: Executive Summary: 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults, Clin. Infect. Dis., 61, 859–863, https://doi.org/10.1093/cid/civ633, 2015. 
Burger, J., Palmowski, Y., Strube, P., Perka, C., Putzier, M., and Pumberger, M.: Low sensitivity of histopathological examination of peri-implant tissue samples in diagnosing postoperative spinal implant infection, Bone Joint J., 102-B, 899–903, https://doi.org/10.1302/0301-620X.102B7.BJJ-2019-1725.R2, 2020. 
Colmenero, J. D., Ruiz-Mesa, J. D., Sanjuan-Jimenez, R., Sobrino, B., and Morata, P.: Establishing the diagnosis of tuberculous vertebral osteomyelitis, Eur. Spine J., 22 Suppl 4, 579–586, https://doi.org/10.1007/s00586-012-2348-2, 2013. 
Czuczman, G. J., Marrero, D. E., Huang, A. J., Mandell, J. C., Ghazikhanian, V., and Simeone, F. J.: Diagnostic yield of repeat CT-guided biopsy for suspected infectious spondylodiscitis, Skeletal Radiol., 47, 1403–1410, https://doi.org/10.1007/s00256-018-2972-y, 2018. 
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Short summary
In this study, we prospectively enrolled patients with a suspected diagnosis of native vertebral osteomyelitis (NVO) undergoing image-guided needle aspiration of the intervertebral disc. Based on this pilot study, a high manual cell count or a high neutrophilic predominance from the disc aspirate was associated with the diagnosis of NVO.