Articles | Volume 7, issue 5
https://doi.org/10.5194/jbji-7-213-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-7-213-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Original full-length article
| 
20 Oct 2022
Original full-length article |
| 20 Oct 2022
| 20 Oct 2022
Utility of disc space aspirate cell counts and differentials in the diagnosis of native vertebral osteomyelitis
Talha Riaz
CORRESPONDING AUTHOR
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota,
USA
Division of Infectious Diseases, University of Arizona Medical Center,
Tucson, Arizona, USA
Matthew Howard
Division of Pathology and Laboratory Medicine, Mayo Clinic, Rochester,
Minnesota, USA
Felix Diehn
Division of Neuroradiology, Mayo Clinic, Rochester, Minnesota, USA
Aaron Joseph Tande
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota,
USA
Courtney Ross
Division of Neuroradiology, Mayo Clinic, Rochester, Minnesota, USA
Paul Huddleston
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota,
USA
Elie Berbari
CORRESPONDING AUTHOR
Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota,
USA
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This paper describes five cases of prosthetic joint infection (PJI) caused by Mycobacterium avium complex (MAC). Infections occurred in both immune competent and immunosuppressed patients. Interestingly, using the Musculoskeletal Infection Society diagnostic criteria for PJI may miss some cases of MAC PJI. Treatment courses and outcomes are described.
Olayinka Ibironke Adebolu, Jennifer Sommer, Abiodun Benjamin Idowu, Nicole Lao, and Talha Riaz
J. Bone Joint Infect., 7, 75–79, https://doi.org/10.5194/jbji-7-75-2022, https://doi.org/10.5194/jbji-7-75-2022, 2022
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This is a case report and literature review that describes Listeria monocytogenes as a rare cause of native vertebral osteomyelitis. This work reviewed previous published cases (nine cases to the best of our knowledge) and documented the clinical course, diagnostic challenges, and treatment of the disease. This case report aims to inform clinicians of the possibility of Listeria monocytogenes invading native joints in patients with or without risk factors.
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The yearly incidence of native vertebral osteomyelitis (NVO) is increasing. In 2013 the prevalence of NVO in the USA was 5.4 cases per 100 000. Delays in the diagnosis of NVO remain common, in part due to the insidious nature of the infection and its related symptoms. The mean time between the onset of symptoms to diagnosis of NVO is 45.5 d. We herein review available and novel diagnostic modalities at the disposal of healthcare providers to reach an accurate and timely diagnosis of NVO.
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This was written to outline Mayo Clinic guidelines on prophylactic antibiotics prior to invasive procedures in patients with prosthetic joints. There is an emphasis on maintaining optimal oral health to reduce the risk of infection to minimize the patient’s risk of PJI.
Talha Riaz, Mark Collins, Mark Enzler, Marco Rizzo, Audrey N. Schuetz, Julia S. Lehman, Douglas Osmon, and Irene G. Sia
J. Bone Joint Infect., 6, 355–361, https://doi.org/10.5194/jbji-6-355-2021, https://doi.org/10.5194/jbji-6-355-2021, 2021
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Tenosynovitis due to Histoplasma capsulatum in an immunocompromised host warrants special attention. Following surgical debridement, the patient initially improved on antifungal therapy, but as immunosuppression was decreased, she presented with a flare, requiring further debridement. With negative fungal cultures and declining antigenemia, it was felt that her interim worsening was as a consequence of immune reconstitution inflammatory syndrome (IRIS).
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J. Bone Joint Infect., 6, 39–42, https://doi.org/10.5194/jbji-6-39-2020, https://doi.org/10.5194/jbji-6-39-2020, 2020
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Short summary
In this study, we prospectively enrolled patients with a suspected diagnosis of native vertebral osteomyelitis (NVO) undergoing image-guided needle aspiration of the intervertebral disc. Based on this pilot study, a high manual cell count or a high neutrophilic predominance from the disc aspirate was associated with the diagnosis of NVO.
In this study, we prospectively enrolled patients with a suspected diagnosis of native vertebral...
