Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 7, issue 2
Articles | Volume 7, issue 2
https://doi.org/10.5194/jbji-7-101-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-7-101-2022
© Author(s) 2022. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 7, issue 2
Original full-length article
 | 
22 Apr 2022
Original full-length article |  | 22 Apr 2022

Prophylaxis and treatment of infection in long bones using an antibiotic-loaded ceramic coating with interlocking intramedullary nails

Emilie-Ann Downey, Kayla M. Jaime, Taylor J. Reif, Asim M. Makhdom, S. Robert Rozbruch, and Austin T. Fragomen

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Latest update: 30 Mar 2025
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Short summary
The use of dissolving local antibiotic delivery systems in orthopedic surgery is improving the way we treat infection. Early analysis of a small cohort suggests that antibiotic-loaded calcium sulfate-coated interlocking intramedullary nails (CS-IMN) are safe and may be as effective as the more established method for infection eradication. Future studies with larger cohorts of patients will be required to confirm these findings.
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