Articles | Volume 6, issue 4
J. Bone Joint Infect., 6, 85–90, 2021
J. Bone Joint Infect., 6, 85–90, 2021
Brief report
27 Jan 2021
Brief report | 27 Jan 2021

Fluorescent tetracycline bone labeling as an intraoperative tool to debride necrotic bone during septic hip revision: a preliminary case series

Ernesto Muñoz-Mahamud et al.

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Cited articles

Bémer, P., Léger, J., Tandé, D., Plouzeau, C., Valentin, A. S., Jolivet-Gougeon, A., Lemarié, C., Kempf, M., Héry-Arnaud, G., Bret, L., Juvin, M. E., Giraudeau, B., Corvec, S., and Burucoa, C.: Centre de Référence des Infections Ostéo-articulaires du Grand Ouest (CRIOGO) Study Team: How Many Samples and How Many Culture Media To Diagnose a Prosthetic Joint Infection: a Clinical and Microbiological Prospective Multicenter Study, J. Clin. Microbiol., 54, 385–391,, 2016. 
Dahners, L. E. and Bos, G. D.: Fluorescent tetracycline labeling as an aid to debridement of necrotic bone in the treatment of chronic osteomyelitis, J Orthop. Trauma., 16, 345–346,, 2002. 
Duwelius, P. J. and Schmidt, A. H.: Assessment of bone viability in patients with osteomyelitis: preliminary clinical experience with laser Doppler flowmetry, J. Orthop. Trauma., 6, 327–332, 1992. 
Giudice, A., Bennardo, F., Barone, S., Antonelli, A., Figliuzzi, L. F., and Fortunato, L.: Can autofluorescence guide surgeons in the treatment of medication-related osteonecrosis of the jaw? A prospective feasibility study, J. Oral Maxillofac. Surg., 76, 982–995, 2018. 
Harvey, B. R., Ephros, H., and Defalco, R. J.: Tetracycline bone labeling in surgical management of chronic osteomyelitis: a case report, J. Oral Maxillofac. Surg., 62, 752–754,, 2004. 
Short summary
A plausible cause of persistent infection after septic hip revision may be the presence of nonviable osteomyelitic bone. We present our initial experience in hip revision for chronic infection in which fluorescent tetracycline bone labeling was used as an additional aid to provide a visual index of surgical bone debridement. In the present series, the use of this technique successfully aided the surgeon to detect the presence of nonviable bone.