Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 6, issue 9
Articles | Volume 6, issue 9
https://doi.org/10.5194/jbji-6-405-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-405-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 9
Original full-length article
 | 
10 Nov 2021
Original full-length article |  | 10 Nov 2021

Fabrication of antibiotic-loaded dissolvable calcium sulfate beads: an in vitro mixing lab utilizing various antibiotic mixing formulas

Edward J. McPherson, Matthew V. Dipane, Madhav Chowdhry, and Andrew J. Wassef

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Latest update: 13 Dec 2024
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Short summary
The use of calcium sulfate as an antibiotic delivery vehicle is a growing treatment option used by surgeons in the face of infection following joint replacement surgery. Calcium sulfate can be mixed with antibiotics and formed into small beads, which can be delivered during surgery to the local site of infection. We performed a mixing study to formalize mixing methods for individual and combined antibiotics with a synthetic calcium sulfate product. We report our mixing formulas and set times.
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