Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 6, issue 8
Articles | Volume 6, issue 8
https://doi.org/10.5194/jbji-6-379-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-6-379-2021
© Author(s) 2021. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 8
Original full-length article
 | 
20 Oct 2021
Original full-length article |  | 20 Oct 2021

Long-term outcome of two-stage revision surgery after hip and knee prosthetic joint infections: an observational study

Yorrick P. Bourgonjen, J. Fred F. Hooning van Duyvenbode, Bruce van Dijk, F. Ruben H. A. Nurmohamed, Ewout S. Veltman, H. Charles Vogely, and Bart C. H. van der Wal

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Cited articles

Bejon, P., Berendt, A., Atkins, B. L., Green, N., Parry, H., Masters, S., McLardy-Smith, P., Gundle, R., and Byren, I.: Two-stage revision for prosthetic joint infection: predictors of outcome and the role of reimplantation microbiology, J. Antimicrob. Chemoth., 65, 569–575, https://doi.org/10.1093/jac/dkp469, 2010. 
Berbari, E. F., Marculescu, C., Sia, I., Lahr, B. D., Hanssen, A. D., and Steckelberg, J. M.: Culture-negative prosthetic joint infection, Clin. Infect. Dis., 45, 1113–1119, https://doi.org/10.1086/522184, 2018. 
Bereza, P. L., Ekiel, A., Augusciak-Duma, A., Aptekorz, M., Wilk, I., Kusz, D. J., Wojciechowski, P., and Martirosian, G.: Identification of silent prosthetic joint infection: preliminary report of a prospective controlled study, Int. Orthop., 37, 2037–2043, https://doi.org/10.1007/s00264-013-1955-9, 2013. 
Choi, H. R., Kwon, Y. M., Freiberg, A. A., Nelson., S. B., and Malchau, H.: Periprosthetic joint infection with negative culture results: clinical characteristics and treatment outcome, J. Arthroplasty, 28, 899–903, https://doi.org/10.1016/j.arth.2012.10.022, 2013. 
de Carvalho, L., Tempon, E., and Badet, R.: Infection after total knee replacement: diagnosis and treatment, Rev. Bras. Orthop., 24, 389–396, https://doi.org/10.1016/j.rboe.2013.01.003, 2013. 
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Short summary
This study provides a comprehensive overview of a frequently used treatment strategy for chronic prosthetic joint infection of the hip and knee. Forty-seven patients met the inclusion criteria. Successful eradication was achieved in 36 of 47 cases. Multiple variables were analysed to explore their influence on the outcome of two-stage revision surgery. No variables were found to have a significant influence. Mean follow-up of over 10 years provides a good perspective of the long-term outcome.
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