Outcomes, Microbiology and Antimicrobial Usage in Pressure Ulcer-Related Pelvic Osteomyelitis: Messages for Clinical Practice

Russell, Clark D.; Tsang, Shao-Ting Jerry; R., Alasdair Hamish; Sutherland, Rebecca K.

doi:https://doi.org/10.7150/jbji.41779

Articles | Volume 5, issue 2

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Articles | Volume 5, issue 2

https://doi.org/10.7150/jbji.41779

Articles | Volume 5, issue 2

Article
Metrics
Related articles

Original full-length article

26 Mar 2020

Original full-length article |

| 26 Mar 2020

Outcomes, Microbiology and Antimicrobial Usage in Pressure Ulcer-Related Pelvic Osteomyelitis: Messages for Clinical Practice

Clark D. Russell, Shao-Ting Jerry Tsang, Alasdair Hamish R., and Rebecca K. Sutherland

Clark D. Russell

NHS Lothian Infection Service, Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, U.K.

University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, U.K.

Shao-Ting Jerry Tsang

University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh BioQuarter, Edinburgh, U.K.

Department of Orthopaedic Surgery, University of Edinburgh, Chancellor's Building, Edinburgh, U.K.

Alasdair Hamish R.

Department of Orthopaedic Surgery, University of Edinburgh, Chancellor's Building, Edinburgh, U.K.

Rebecca K. Sutherland

CORRESPONDING AUTHOR

NHS Lothian Infection Service, Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, U.K.

Cited articles

Cunha BA. Osteomyelitis in elderly patients. Clin Infect Dis. 2002;35:287–93.

Han H, Lewis VL Jr, Wiedrich TA, Patel PK. The value of Jamshidi core needle bone biopsy in predicting postoperative osteomyelitis in grade IV pressure ulcer patients. Plast Reconstr Surg. 2002;110:118–22.

Wong D, Holtom P, Spellberg B. Osteomyelitis Complicating Sacral Pressure Ulcers: Whether or Not to Treat With Antibiotic Therapy. Clin Infect Dis. 2019;68:338–42. [PMC free article]

Turk EE, Tsokos M, Delling G. Autopsy-based assessment of extent and type of osteomyelitis in advanced-grade sacral decubitus ulcers: a histopathologic study. Arch Pathol Lab Med. 2003;127:1599–602.

Darouiche RO, Landon GC, Klima M, Musher DM, Markowski J. Osteomyelitis associated with pressure sores. Arch Intern Med. 1994;154:753–8.

Sugarman B, Hawes S, Musher DM, Klima M, Young EJ, Pircher F. Osteomyelitis beneath pressure sores. Arch Intern Med. 1983;143:683–8.

Brunel AS, Lamy B, Cyteval C, Perrochia H, Teot L, Masson R. et al. Diagnosing pelvic osteomyelitis beneath pressure ulcers in spinal cord injured patients: a prospective study. Clin Microbiol Infect. 2016;22:267.e1–8.

Larson DL, Gilstrap J, Simonelic K, Carrera GF. Is there a simple, definitive, and cost-effective way to diagnose osteomyelitis in the pressure ulcer patient? Plast Reconstr Surg. 2011;127:670–6.

Lewis VL Jr, Bailey MH, Pulawski G, Kind G, Bashioum RW, Hendrix RW. The diagnosis of osteomyelitis in patients with pressure sores. Plast Reconstr Surg. 1988;81:229–32.

Dudareva M, Ferguson J, Riley N, Stubbs D, Atkins B, McNally M. Osteomyelitis of the Pelvic Bones: A Multidisciplinary Approach to Treatment. J Bone Jt Infect. 2017;2:184–93. [PMC free article]

Greenky M, Gandhi K, Pulido L, Restrepo C, Parvizi J. Preoperative anemia in total joint arthroplasty: is it associated with periprosthetic joint infection? Clin Orthop Relat Res. 2012;470:2695–701. [PMC free article]

Myers E, Grady PO, Dolan AM. The influence of preclinical anaemia on outcome following total hip replacement. Arch Orthop Trauma Surg. 2004;124:699–701.

Morales CH, Escobar RM, Villegas MI, Castaño A, Trujillo J. Surgical site infection in abdominal trauma patients: risk prediction and performance of the NNIS and SENIC indexes. Can J Surg. 2011;54:17–24. [PMC free article]

Steinitz D, Harvey EJ, Leighton RK, Petrie DP. Is homologous blood transfusion a risk factor for infection after hip replacement? Can J Surg. 2001;44:355–8. [PMC free article]

Alexander JW, Solomkin JS, Edwards MJ. Updated recommendations for control of surgical site infections. Ann Surg. 2011;253:1082–93.

Lavernia CJ, Sierra RJ, Baerga L. Nutritional Parameters and Short Term Outcome in Arthroplasty. J Am Coll Nutr. 1999;18:274–8.

Gherini S, Vaughn BK, Lombardi AV, Mallory TH. Delayed wound healing and nutritional deficiencies after total hip arthroplasty. Clin Orthop Relat Res. 1993;293:188–95.

Cross MB, Yi PH, Thomas CF, Garcia Ja. Evaluation of Malnutrition in Orthopaedic Surgery. J Am Acad Orthop Surg. 2014;22:193–9.

McLaren AC, Lundy DW. AAOS Systematic Literature Review: Summary on the Management of Surgical Site Infections. J Am Acad Orthop Surg. 2018;27:e717–20.

Del Savio GC, Zelicof SB, Wexler LM, Byrne DW, Reddy PD, Fish D. et al. Preoperative nutritional status and outcome of elective total hip replacement. Clin Orthop Relat Res. 1996;326:153–61.

Yuwen P, Chen W, Lv H, Feng C, Li Y, Zhang T. et al. Albumin and surgical site infection risk in orthopaedics: a meta-analysis. BMC Surg. 2017;17:7. [PMC free article]

Zainul-Abidin S, Amanatullah DF, Anderson MB, Austin M, Barretto JM, Battenberg A. et al. General Assembly, Prevention, Host Related General: Proceedings of International Consensus on Orthopedic Infections. J Arthroplasty. 2019;34:s13–35.

Chotanaphuti T, Courtney PM, Fram B, In den Kleef NJ, Kim TK, Kuo FC. et al. Hip and Knee Section, Treatment, Algorithm: Proceedings of International Consensus on Orthopedic Infections. J Arthroplasty. 2019;34:s393–7.

Azboy I, Bedair H, Demirtas A, Ford E, Gahramanov A, Klement MR. et al. General Assembly, Prevention, Risk Mitigation, General Factors: Proceedings of International Consensus on Orthopedic Infections. J Arthroplasty. 2019;34:s55–9.

Prez-Guisado J, de Haro-Padilla JM, Rioja LF, Derosier LC, de la Torre JI. Serum albumin levels in burn people are associated to the total body surface burned and the length of hospital stay but not to the initiation of the oral/enteral nutrition. Int J Burns Trauma. 2013;3:159–63. [PMC free article]

Marriott R, Rubayi S. Successful Truncated Osteomyelitis Treatment for Chronic Osteomyelitis Secondary to Pressure Ulcers in Spinal Cord Injury Patients. Ann Plast Surg. 2008;61:425–9.

Jugun K, Richard J-C, Lipsky BA, Kressmann B, Pittet-Cuenod B, Suv. Factors Associated With Treatment Failure of Infected Pressure Sores. Ann Surg. 2016;264:399–403.

Bodavula P, Liang SY, Wu J, VanTassell P, Marschall J. Pressure Ulcer-Related Pelvic Osteomyelitis: A Neglected Disease? Open Forum Infect Dis. 2015;2:112. [PMC free article]

Wouthuyzen-Bakker M, Sebillotte M, Lomas J, Taylor A, Palomares EB, Murillo O. et al. Clinical outcome and risk factors for failure in late acute prosthetic joint infections treated with debridement and implant retention. J Infect. 2019;78:40–7.

Markanday A. Acute Phase Reactants in Infections: Evidence-Based Review and a Guide for Clinicians. Open Forum Infect Dis. 2015;2:98. [PMC free article]

Wong D, Holtom P, Spellberg B. Osteomyelitis complicating sacral pressure ulcers: whether or not to treat with antibiotic therapy. Clin Infect Dis. 2018;68:338–42. [PMC free article]

Yan CH, Arciola CR, Soriano A, Levin LS, Bauer TW, Parvizi J. Team Approach: The Management of Infection After Total Knee Replacement. JBJS Rev. 2018;6:e9.

Jugun K, Richard JC, Lipsky BA, Kressmann B, Pittet-Cuenod B, Suva D. et al. Factors Associated With Treatment Failure of Infected Pressure Sores. Ann Surg. 2016;264:399–403.

Firriolo JM, Ganske IM, Pike CM, Caillouette C, Faulkner HR, Upton J 3rd. et al. Long-term Outcomes After Flap Reconstruction in Pediatric Pressure Ulcers. Ann Plast Surg. 2018;80:159–63.

Li HK, Rombach I, Zambellas R, Walker AS, McNally MA, Atkins BL. et al. Oral versus Intravenous Antibiotics for Bone and Joint Infection. N Engl J Med. 2019;380:425–36. [PMC free article]

Ramesh R, Gaston MS, Simpson AHRW. Chronic osteomyelitis of the pelvis. Acta Orthop Belg. 2013;79:280–6.