Journal cover Journal topic
Journal of Bone and Joint Infection An open-access journal of the European Bone and Joint Infection Society and the MusculoSkeletal Infection Society
Journal topic

Journal metrics

h5-index value: 15
h5-index15
Volume 4, issue 6
J. Bone Joint Infect., 4, 280–284, 2019
https://doi.org/10.7150/jbji.35424
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
J. Bone Joint Infect., 4, 280–284, 2019
https://doi.org/10.7150/jbji.35424
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.

Original full-length article 07 Nov 2019

Original full-length article | 07 Nov 2019

Humoral Factors From Musculoskeletal Polytrauma Patients Impair Antibacterial Responses Of Neutrophils In vitro

Aikaterini Stylianaki1, Barbara Stanic1, Mario Morgenstern2, Geoff R. Richards1, Fintan T. Moriarty1, and Keith Thompson1 Aikaterini Stylianaki et al.
  • 1AO Research Institute Davos, Davos, Switzerland.
  • 2Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland.

Keywords: polytrauma, neutrophil, antibacterial activity

Abstract. Polytrauma is associated with increased risk of sepsis, but the risk for implant infection is less clear. Neutrophil antibacterial responses are significantly reduced in polytrauma patients (n= 9, ISS≥15) for at least 5 days compared to healthy controls. Reduced neutrophil activity could influence implant infection in addition to sepsis.

Publications Copernicus
Download
Citation