JBJI Journal of Bone and Joint Infection JBJI J. Bone Joint Infect. 2206-3552 Ivyspring Göttingen, Germany 10.7150/jbji.35424 Humoral Factors From Musculoskeletal Polytrauma Patients Impair Antibacterial Responses Of Neutrophils <em>In vitro</em> Stylianaki Aikaterini 1 Stanic Barbara 1 Morgenstern Mario 2 Richards Geoff R. 1 Moriarty Fintan T. 1 Thompson Keith 1 AO Research Institute Davos, Davos, Switzerland. Department of Orthopaedic and Trauma Surgery, University Hospital Basel, Switzerland. 07 11 2019 4 6 280 284 Copyright: © 2019 Aikaterini Stylianaki et al. 2019 This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/ This article is available from https://jbji.copernicus.org/articles/4/280/2019/jbji-4-280-2019.html The full text article is available as a PDF file from https://jbji.copernicus.org/articles/4/280/2019/jbji-4-280-2019.pdf

<p class="p p-first-last" id="__p2">Polytrauma is associated with increased risk of sepsis, but the risk for implant infection is less clear. Neutrophil antibacterial responses are significantly reduced in polytrauma patients (n= 9, ISS≥15) for at least 5 days compared to healthy controls. Reduced neutrophil activity could influence implant infection in addition to sepsis.</p>

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