Articles | Volume 4, issue 6
https://doi.org/10.7150/jbji.35424
https://doi.org/10.7150/jbji.35424
Original full-length article
 | 
07 Nov 2019
Original full-length article |  | 07 Nov 2019

Humoral Factors From Musculoskeletal Polytrauma Patients Impair Antibacterial Responses Of Neutrophils In vitro

Aikaterini Stylianaki, Barbara Stanic, Mario Morgenstern, Geoff R. Richards, Fintan T. Moriarty, and Keith Thompson

Keywords: polytrauma, neutrophil, antibacterial activity

Abstract. Polytrauma is associated with increased risk of sepsis, but the risk for implant infection is less clear. Neutrophil antibacterial responses are significantly reduced in polytrauma patients (n= 9, ISS≥15) for at least 5 days compared to healthy controls. Reduced neutrophil activity could influence implant infection in addition to sepsis.