Articles | Volume 3, issue 4
https://doi.org/10.7150/jbji.27811
https://doi.org/10.7150/jbji.27811
Original full-length article
 | 
04 Oct 2018
Original full-length article |  | 04 Oct 2018

Daptomycin Plus Fosfomycin as Salvage Therapy in a Difficult-to-Treat Total Femoral Replacement Infection

Gonzalo Luengo, Jaime Lora-Tamayo, Diana Paredes, Irene Muñoz-Gallego, Antonio Díaz, and Emilio Delgado

Keywords: prosthetic joint infection, biofilm, Staphylococcus, bone and joint infection

Abstract. The highly active anti-biofilm combination of daptomycin plus fosfomycin was successfully used in a difficult-to-treat infection of a total femoral replacement caused by multi-drug resistant Staphylococcus epidermidis in a 79-year-old woman. There was no need to remove the orthopedic hardware, and the patient is currently pain free and able to walk.