94 citations as recorded by crossref.

1. Articulating spacers: what are available and how to utilize them? Z. Li et al. https://doi.org/10.1186/s42836-023-00167-6
2. Nanoporous 3D-Printed Scaffolds for Local Doxorubicin Delivery in Bone Metastases Secondary to Prostate Cancer P. Ahangar et al. https://doi.org/10.3390/ma11091485
3. Low dose vancomycin-loaded spacers for two-stage revision knee arthroplasty: High success, low toxicity E. Dedeogullari et al. https://doi.org/10.1016/j.knee.2022.11.008
4. Systematic review of single stage revision for prosthetic joint infection Z. Lum et al. https://doi.org/10.5312/wjo.v11.i12.559
5. Effects of storage up to 1 year on the in vitro antimicrobial activity of preformulated antibiotic‐impregnated calcium sulfate beads E. Hartman et al. https://doi.org/10.1111/vsu.14014
6. 3D printing in experimental orthopaedic surgery: do it yourself I. López-Torres et al. https://doi.org/10.1007/s00590-019-02415-5
7. Addressing Antibiotic Hip Spacer Instability via Hybrid Screw-cement Fixation of a Constrained Liner and Cement-rebar Interface Techniques: A Technical Narrative J. Patel et al. https://doi.org/10.5435/JAAOS-D-19-00116
8. Two stage surgical treatment of cuboid osteomyelitis. A case report and review of the literature E. Vasiliadis et al. https://doi.org/10.1016/j.foot.2021.101796
9. Küntscher nails with static cement spacer: A simple technique in periprosthetic knee infections with massive bone loss and instability M. Lo Presti et al. https://doi.org/10.1016/j.knee.2021.01.025
10. Les spacers dans la prise en charge en deux temps des infections péri-prothétiques C. Batailler et al. https://doi.org/10.1016/j.rcot.2024.06.018
11. Research Progress of Antibiotic-Loaded Bone Cement in Treating Infected Wounds 梓. 郝 https://doi.org/10.12677/ACM.2023.135994
12. Ciprofloxacin‐Loaded, pH‐Responsive PAMAM‐Megamers Functionalized with S‐Nitrosylated Hyaluronic Acid Support Infected Wound Healing in Mice without Inducing Antibiotic Resistance G. Jiang et al. https://doi.org/10.1002/adhm.202301747
13. Articulating Hip Spacers with a Constrained Acetabular Liner: Effect of Acetabular Bone Loss and Cementation Quality G. Glenn et al. https://doi.org/10.3390/antibiotics12091384
14. Local Antibiotic Delivery Systems and Their Applications in Orthopaedic Surgery A. Hoveidaei et al. https://doi.org/10.2106/JBJS.OA.25.00157
15. Efficacy of Antibiotic‐Loaded Hydroxyapatite/Collagen Composites Is Dependent on Adsorbability for Treating Staphylococcus aureus Osteomyelitis in Rats S. Egawa et al. https://doi.org/10.1002/jor.24507
16. Evaluation and Management of a Painful Knee After Total Knee Arthroplasty A. Cooper et al. https://doi.org/10.3928/01477447-20211001-08
17. Routine use of antibiotic‐laden bone cement in total knee arthroplasty is a cost‐effective practice in the single‐payer healthcare system H. Abdel Khalik et al. https://doi.org/10.1007/s00167-023-07364-5
18. Does spiked tibial cement spacer reduce spacer-related problems in two-stage revision total knee arthroplasty for infection? K. Jung et al. https://doi.org/10.1007/s00264-022-05438-6
19. Periprosthetic joint infection after arthroplasty: advances and future prospects X. Xiong et al. https://doi.org/10.1186/s13018-025-06257-2
20. 2025 ICM: Spacers B. Fink et al. https://doi.org/10.1016/j.arth.2025.10.106
21. Antibiotic-loaded cement spacers – lessons learned from the past 20 years K. Anagnostakos & B. Fink https://doi.org/10.1080/17434440.2018.1435270
22. In Vitro Study on the Degradation Behavior of Different Antibiotic-Loaded Biomaterials for Orthopedic Applications I. Antoniac et al. https://doi.org/10.3390/app16052242
23. Trimethoprim Combined With Vancomycin and Gentamicin Composite Bone Cement In Vitro R. Guo et al. https://doi.org/10.1097/MAT.0000000000002578
24. Safety Profile of Seven-Day Intra-articular Antibiotic Irrigation for the Treatment of Chronic Periprosthetic Joint Infection: A Prospective Randomized Phase II Comparative Study B. Springer et al. https://doi.org/10.1016/j.arth.2024.03.069
25. Impact of Manual Addition of Vancomycin to Polymethylmethacrylate (PMMA) Cements C. Kittinger et al. https://doi.org/10.3390/antibiotics13080721
26. The Role of Poly(Methyl Methacrylate) in Management of Bone Loss and Infection in Revision Total Knee Arthroplasty: A Review L. Hasandoost et al. https://doi.org/10.3390/jfb11020025
27. Are Cement Spacers and Beads Loaded with the Correct Antibiotic(s) at the Site of Periprosthetic Hip and Knee Joint Infections? K. Anagnostakos & I. Sahan https://doi.org/10.3390/antibiotics10020143
28. Augmented Articulating Spacers in Infected Total Knee Arthroplasty: Surgical Technique D. De Mauro et al. https://doi.org/10.3390/healthcare12070735
29. Antibiotic Elution from Cement Spacers and Its Influencing Factors B. Fink & K. Tetsworth https://doi.org/10.3390/antibiotics14070705
30. Polymethyl methacrylate‐based bone cement using a prototype for gingival smile: A case report B. Rodriguez‐Mannucci et al. https://doi.org/10.1002/cap.10322
31. DRESS syndrome induced by antibiotic-loaded bone cements and a diagnostic algorithm for related delayed-type hypersensitivity reactions V. Chiang et al. https://doi.org/10.1016/j.jaip.2020.09.040
32. In Situ Generated Medical Devices D. Cohn et al. https://doi.org/10.1002/adhm.201801066
33. Mechanical Integrity Assessment of Polymethylmethacrylate Bone Cement Incorporating Local Anesthetics: Implications for Joint Arthroplasty M. Monfort-Mira et al. https://doi.org/10.1016/j.arth.2025.01.014
34. Toward Designing of Anti-infective Hydrogels for Orthopedic Implants: From Lab to Clinic D. Garg et al. https://doi.org/10.1021/acsbiomaterials.0c01408
35. The efficacy of antibiotic‐eluting material in a two‐stage model of periprosthetic joint infection Y. Fan et al. https://doi.org/10.1002/jor.25681
36. The heavy burden and treatment challenges of fungal periprosthetic joint infection: a systematic review of 489 joints G. Shang et al. https://doi.org/10.1186/s12891-024-07616-6
37. Impact of saline irrigation on the early mechanical characteristics and microstructure of bone cement S. Kazemi et al. https://doi.org/10.1038/s41598-024-82737-5
38. LbL-assembled gentamicin delivery system for PMMA bone cements to prolong antimicrobial activity Y. Al Thaher et al. https://doi.org/10.1371/journal.pone.0207753
39. Hip and Knee Section, Treatment, Prosthesis Factors: Proceedings of International Consensus on Orthopedic Infections G. Bori et al. https://doi.org/10.1016/j.arth.2018.09.030
40. Current Concepts on the Application, Pharmacokinetics and Complications of Antibiotic-Loaded Cement Spacers in the Treatment of Prosthetic Joint Infections P. Samelis et al. https://doi.org/10.7759/cureus.20968
41. Influence of biofilm growth age, media, antibiotic concentration and exposure time on Staphylococcus aureus and Pseudomonas aeruginosa biofilm removal in vitro X. Chen et al. https://doi.org/10.1186/s12866-020-01947-9
42. A meta-analysis of bone cement mediated antibiotic release: Overkill, but a viable approach to eradicate osteomyelitis and other infections tied to open procedures L. Mensah & B. Love https://doi.org/10.1016/j.msec.2021.111999
43. Antibiotic-loaded cement in total joint arthroplasty: a comprehensive review A. Fraval et al. https://doi.org/10.1007/s00402-024-05328-z
44. Linear IgA bullous dermatosis protracted by vancomycin-loaded bone cement N. Nartker et al. https://doi.org/10.1016/j.jdcr.2019.01.011
45. Short-term outcomes of articular cement spacer in the treatment of prosthetic knee joint infections: a retrospective case series P. Yeo et al. https://doi.org/10.4103/singaporemedj.SMJ-2021-389
46. Cephalomedullary Nail as a Definitive Antibiotic Spacer for Multidrug Resistant Periprosthetic Infection of a Proximal Femoral Endoprosthesis J. Connors et al. https://doi.org/10.1097/BTO.0000000000000559
47. Properties of Orthopaedic Cements Biomechanically Little Affected by Exceptional Use of Liquid Antibiotics H. Sophie et al. https://doi.org/10.1111/os.12911
48. Is sonication of antibiotic-loaded cement spacers useful in two-stage revision of prosthetic joint infection? A. Sambri et al. https://doi.org/10.1016/j.mimet.2018.12.006
49. Stratégie en deux temps et spacers dans les révisions de PTG infectées C. Batailler et al. https://doi.org/10.1016/j.rcot.2026.03.005
50. An Additive to PMMA Bone Cement Enables Postimplantation Drug Refilling, Broadens Range of Compatible Antibiotics, and Prolongs Antimicrobial Therapy E. Cyphert et al. https://doi.org/10.1002/adhm.201800812
51. Antifungal-Loaded Acrylic Bone Cement in the Treatment of Periprosthetic Hip and Knee Joint Infections: A Review K. Anagnostakos et al. https://doi.org/10.3390/antibiotics11070879
52. Spacers in two-stage strategy for periprosthetic infection C. Batailler et al. https://doi.org/10.1016/j.otsr.2024.104074
53. Pseudomonas aeruginosa biofilm killing beyond the spacer by antibiotic-loaded calcium sulfate beads: an in vitro study J. Brooks et al. https://doi.org/10.5194/jbji-6-119-2021
54. PMMA Bone Cement: Antibiotic Elution and Mechanical Properties in the Context of Clinical Use S. von Hertzberg-Boelch et al. https://doi.org/10.3390/biomedicines10081830
55. Resection of the proximal femur during one-stage revision for infected hip arthroplasty H. Abdelaziz et al. https://doi.org/10.1302/0301-620X.103B11.BJJ-2021-0022.R1
56. Colistin-containing cement spacer for treatment of experimental carbapenemase-producing Klebsiella pneumoniae prosthetic joint infection L. Gatin et al. https://doi.org/10.1016/j.ijantimicag.2019.07.009
57. Complications in hip surgery A. Riemen & C. Munro https://doi.org/10.1016/j.mporth.2019.10.003
58. Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence C. Berberich et al. https://doi.org/10.5312/wjo.v12.i3.119
59. The effect of different antibiotic combinations in calcium sulfate cement on the growth of Cutibacterium acnes and Staphylococcus periprosthetic shoulder infection isolates T. Listopadzki et al. https://doi.org/10.1016/j.jse.2024.01.021
60. Real-implant articulating spacers for chronic knee prosthetic joint infection have similar infection control rates as all-cement spacer constructs J. Wong et al. https://doi.org/10.1016/j.knee.2025.08.001
61. Comparison of Elution Characteristics and Compressive Strength of Biantibiotic-Loaded PMMA Bone Cement for Spacers: Copal® Spacem with Gentamicin and Vancomycin versus Palacos® R+G with Vancomycin S. Boelch et al. https://doi.org/10.1155/2018/4323518
62. Local Antimicrobial Treatment in Orthopaedic Surgery A. Chen & H. Winkler https://doi.org/10.7150/jbji.9465
63. Release of different amphotericin B formulations from PMMA bone cements and their activity against Candida biofilm M. Czuban et al. https://doi.org/10.1016/j.colsurfb.2019.110406
64. The Effect of TBB, as an Initiator, on the Biological Compatibility of PMMA/MMA Bone Cement K. Hamajima et al. https://doi.org/10.3390/ijms21114016
65. Management of Foreign Organic Material Identified During Primary Total Knee Arthroplasty Z. Radford et al. https://doi.org/10.2106/JBJS.CC.21.00393
66. Antibiotic-impregnated bone cement for preventing infection in patients receiving primary total hip and knee arthroplasty J. Zhang et al. https://doi.org/10.1097/MD.0000000000018068
67. Modified Hofmann Articulated Spacer in the Treatment of Peri-Prosthetic Joint Infection of the Knee—Surgical Technique and Early Clinical Evaluation S. Risitano et al. https://doi.org/10.3390/jcm14217605
68. Vancomycin-Gentamicin Prefabricated Spacers in 2-Stage Revision Arthroplasty for Chronic Hip and Knee Periprosthetic Joint Infection: Insights Into Reimplantation Microbiology and Outcomes S. Corró et al. https://doi.org/10.1016/j.arth.2019.07.043
69. Increased Detection of Polymicrobial Infections by Sonication and Significance of Prosthesis Design and Fixation Technique in Cases of Low-Grade PJI, a Retrospective Study N. Haustedt et al. https://doi.org/10.4236/ojo.2020.1010028
70. In vitro study of elution kinetics and biological activity of piperacillin/tazobactam and gentamicin in acrylic bone cement T. Goyal et al. https://doi.org/10.1016/j.otsr.2022.103230
71. Antibiotic Release and Mechanical Performance of Polymethylmethacrylate (PMMA) Bone Cement: Findings from In-vitro Studies M. Karaglani https://doi.org/10.46889/JOSR.2024.5308
72. Outcomes of Articulating Spacers With Autoclaved Femoral Components in Total Knee Arthroplasty Infection D. Goltz et al. https://doi.org/10.1016/j.arth.2018.03.059
73. In vitro elution of amikacin and Dispersin B from a polymer hydrogel C. Hagen et al. https://doi.org/10.1111/vsu.13421
74. Vancomycin elution from a biphasic ceramic bone substitute M. Stravinskas et al. https://doi.org/10.1302/2046-3758.82.BJR-2018-0174.R2
75. Preliminary tribological results of a new total temporary hip joint prosthesis spacer C. González Rivera et al. https://doi.org/10.1177/09544119221117965
76. Antibiotic cement-coated plate is a viable and efficient technique for the definitive management of metaphyseal septic nonunions of the femur and tibia F. BIDOLEGUI et al. https://doi.org/10.1590/0100-6991e-20223060-en
77. Handmade spacers for two-stage exchange at the hip S. von Hertzberg-Bölch et al. https://doi.org/10.1007/s00064-023-00811-z
78. Analysis of Corrosion Behavior and Surface Properties of Plasma-Sprayed HA/Ta Coating on CoCr Alloy B. Singh et al. https://doi.org/10.1007/s11666-018-0786-z
79. Modification of the Polymer of a Bone Cement with Biodegradable Microspheres of PLGA and Loading with Daptomycin and Vancomycin Improve the Response to Bone Tissue Infection J. García-García et al. https://doi.org/10.3390/polym14050888
80. Antimicrobial PMMA Bone Cement Containing Long Releasing Multi-Walled Carbon Nanotubes Y. Al Thaher et al. https://doi.org/10.3390/nano12081381
81. Timely explantation of tobramycin-impregnated beads and bone cement to avoid haemodialysis in a patient with worsening renal failure J. Borick et al. https://doi.org/10.1136/bcr-2021-242760
82. Selected Heat-Sensitive Antibiotics Are Not Inactivated During Polymethylmethacrylate Curing and Can Be Used in Cement Spacers for Periprosthetic Joint Infection A. Carli et al. https://doi.org/10.1016/j.arth.2018.01.034
83. Successful glenoid defect management with antibiotic-eluting bone graft substitute following baseplate removal in two-stage revision reverse shoulder arthroplasty: a case report and surgical considerations E. Beijer et al. https://doi.org/10.1016/j.xrrt.2026.100866
84. Antimicrobial Regimens in Cement Spacers for Periprosthetic Joint Infections: A Critical Review S. Naoum et al. https://doi.org/10.3390/antibiotics13080772
85. Elution of antibiotics from bone cement: problems and ways to solution R. Shafigulin et al. https://doi.org/10.18019/1028-4427-2025-31-1-119-128
86. O uso de placas revestidas de cimentado com antibiótico é uma técnica viável e eficiente para o tratamento da pseudoartrose infectada da metáfise do fêmur e da tíbia F. BIDOLEGUI et al. https://doi.org/10.1590/0100-6991e-20223060
87. Cement Beads at First Stage Improve Femoral Endosteal Recovery: A Comparative Study of Revision and Primary Taper Slip Femoral Components J. Shelton et al. https://doi.org/10.1055/s-0042-1757327
88. Cemented prosthesis as spacer for two-stage revision of infected hip prostheses: a similar infection remission rate and a lower complication rate W. Zhang et al. https://doi.org/10.1302/2046-3758.98.BJR-2020-0173
89. Comparison of elution characteristics and mechanical properties of acrylic bone cements with and without superficial vancomycin coating (SVC) in the late phase of polymerization V. Labmayr et al. https://doi.org/10.1016/j.otsr.2021.102908
90. Antibiotic-Loaded Bone Cement in Primary Total Knee Arthroplasty: Utilization Patterns and Impact on Complications Using a National Database J. Chan et al. https://doi.org/10.1016/j.arth.2019.03.006
91. Antibiotic-loaded bone cement M. Svoboda et al. https://doi.org/10.36290/far.2017.024
92. A call for action to the biomaterial community to tackle antimicrobial resistance T. Hall et al. https://doi.org/10.1039/D0BM01160F
93. A comparison of low-dose teicoplanin-loaded spacer application vs. high-dose vancomycin-and-gentamicin-loaded spacer application in the treatment of periprosthetic knee infection O. Cimen et al. https://doi.org/10.1177/22104917221082312
94. Effects of Component Prechilling and Ambient Temperature on the Handling and Thermal Characteristics of Two Polymethylmethacrylate (PMMA) Bone Cements S. Gergo et al. https://doi.org/10.7759/cureus.117784