Articles | Volume 11, issue 3
https://doi.org/10.5194/jbji-11-343-2026
© Author(s) 2026. This work is distributed under the Creative Commons Attribution 4.0 License.
Review
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12 Jun 2026
Review |
| 12 Jun 2026
| 12 Jun 2026
Intrawound vancomycin powder in orthopaedic surgery after the VPIP trial: a critical reappraisal of efficacy, dosing, application plane, and antimicrobial stewardship
Related authors
J. Bone Joint Infect., 10, 609–615, 2025
Cited articles
Anemüller, R., Belden, K., Brause, B., Citak, M., Del Pozo, J. L., Frommelt, L., Gehrke, T., Hewlett, A., Higuera, C. A., Hughes, H., Kheir, M., Kim, K.-I., Konan, S., Lausmann, C., Marculescu, C., Morata, L., Ramirez, I., Rossmann, M., Silibovsky, R., Soriano, A., Suh, G. A., Vogely, C., Volpin, A., Yombi, J., Zahar, A., and Zimmerli, W.: Hip and knee section, treatment, antimicrobials, in: Proceedings of the International Consensus Meeting on Musculoskeletal Infection, J. Arthroplasty, 34, S463–S475, https://doi.org/10.1016/j.arth.2018.09.032, 2019.
Berríos-Torres, S. I., Umscheid, C. A., Bratzler, D. W., Leas, B., Stone, E. C., Kelz, R. R., Reinke, C. E., Morgan, S., Solomkin, J. S., Mazuski, J. E., Dellinger, E. P., Itani, K. M. F., Berbari, E. F., Segreti, J., Parvizi, J., Blanchard, J., Allen, G., Kluytmans, J. A. J. W., Donlan, R., and Schecter, W. P.: Centers for Disease Control and Prevention guideline for the prevention of surgical site infection, 2017, JAMA Surg., 152, 784–791, https://doi.org/10.1001/jamasurg.2017.0904, 2017.
Beschauner, J., Felsberg, M., Zeh, A., Delank, K.-S., Gutteck, N., and Werneburg, F.: Renal safety of intraoperative local vancomycin powder application in orthopedic surgery: a retrospective analysis, J. Bone Joint Infect., 10, 609–615, https://doi.org/10.5194/jbji-10-609-2025, 2025.
Brothers, K. M., Parker, D. M., Taguchi, M., Ma, D., Mandell, J. B., Thurlow, L. L., Byrapogu, V. C., and Urish, K. L.: Dose optimization in surgical prophylaxis: sub-inhibitory dosing of vancomycin increases rates of biofilm formation and the rates of surgical site infection, Sci. Rep., 13, 4593, https://doi.org/10.1038/s41598-023-30951-y, 2023.
Caroom, C., Tullar, J. M., Benton Jr., E. G., Jones, J. R., and Chaput, C. D.: Intrawound vancomycin powder reduces surgical site infections in posterior cervical fusion, Spine, 38, 1183–1187, https://doi.org/10.1097/BRS.0b013e31828fcfb5, 2013.
