Articles | Volume 11, issue 3
https://doi.org/10.5194/jbji-11-315-2026
https://doi.org/10.5194/jbji-11-315-2026
Original full-length article
 | 
03 Jun 2026
Original full-length article |  | 03 Jun 2026

Tapping our resources: do preoperative aspirations add diagnostic value in hip and knee periprosthetic joint infection?

Anne Spichler-Moffarah, Lauren Daddi, Ilda Molloy, Tyler Luu, Duc Nguyen, and Marjorie Golden

Cited articles

Akkaya, M., Zanna, L., Sangaletti, R., Bokhari, A., Gehrke, T., and Citak, M.: What Is the Most Reliable Concordance Rate of Preoperative Synovial Fluid Aspiration and Intraoperative Biopsy to Detect Periprosthetic Joint Infection in Knee, Hip and Shoulder Arthroplasty?, Antibiotics, 12, https://doi.org/10.3390/antibiotics12101482, 2023. 
Boyle, K. K., Kapadia, M., Chiu, Y. F., Khilnani, T., Miller, A. O., Henry, M. W., Lyman, S., and Carli, A. V.: The James A. Rand Young Investigator's Award: Are Intraoperative Cultures Necessary If the Aspiration Culture Is Positive? A Concordance Study in Periprosthetic Joint Infection, J. Arthroplasty, 36, S4–S10, https://doi.org/10.1016/j.arth.2021.01.073, 2021. 
Li, H., Xu, C., Hao, L., Chai, W., Jun, F., and Chen, J.: The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not, BMC Infect. Dis., 21, 1018, 2021. 
Matter-Parrat, V., Ronde-Oustau, C., Boéri, C., Gaudias, J., and Jenny, J. Y.: Agreement between preoperative and intra-operative bacteriological samples in 85 chronic peri-prosthetic infections, Orthop. Traumatol. Surg. Res., 103, 301–305, https://doi.org/10.1016/j.otsr.2016.11.022, 2017. 
McNally, M., Sousa, R., Wouthuyzen-Bakker, M., Chen, A. F., Soriano, A., Vogely, H. C., Clauss, M., Higuera, C. A., and Trebše, R.: The EBJIS definition of periprosthetic joint infection, Bone Joint J., 103-b, 18–25, https://doi.org/10.1302/0301-620x.103b1.Bjj-2020-1381.R1, 2021.  
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Short summary
This is a study that included our daily practice with a cohort of patients with prosthetic joint infection (PJI) of the knee or hip, that had admissions with concern for PJI, and had surgery for that. Synovial aspiration and cultures were compared with intraoperative culture results. Our concordance rate (yielding the same organism(s) or if both were negative) between synovial and intraoperative cultures was almost 75 %, with low frequency of culture-negative and few polymicrobial PJI.  
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