Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 11, issue 2
Articles | Volume 11, issue 2
https://doi.org/10.5194/jbji-11-247-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-11-247-2026
© Author(s) 2026. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 11, issue 2
Original full-length article
 | 
27 Apr 2026
Original full-length article |  | 27 Apr 2026

Blood gas analyzers enable reliable measurement of synovial pH, lactate, and glucose in native and periprosthetic joint infection: an analytical agreement study

Dirk Müller, Igor Lazic, Benjamin Schloßmacher, Vincent Lallinger, Christian Wendler, Rüdiger von Eisenhart-Rothe, and Susanne Weber

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Cited articles

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Brennan, M. B. and Hsu, J. L.: Septic arthritis in the native joint, Curr. Infect. Dis. Rep., 14, 558–565, 10.1007/s11908-012-0285-1, 2012. 
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Short summary
Synovial pH, lactate, and glucose are established biomarkers for joint infection but are usually analyzed in central laboratories. In this prospective analytical agreement study, we evaluated whether blood gas analyzers can measure these parameters at the point of care. Blood gas analyzer measurements showed good to excellent agreement with laboratory reference methods, particularly for lactate and glucose, supporting their use for rapid diagnosis of native and periprosthetic joint infection.
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