Articles | Volume 11, issue 2
https://doi.org/10.5194/jbji-11-219-2026
https://doi.org/10.5194/jbji-11-219-2026
Review
 | 
13 Apr 2026
Review |  | 13 Apr 2026

Twenty common errors in the prevention, diagnosis, and treatment of fracture-related infection (FRI)

Goran Georgievski, Nike Walter, Ronald Man Yeung Wong, Irene Katharina Sigmund, Ashok Kanuri, Christian Heiss, and Markus Rupp

Related authors

Investigating long-term quality of life and depressive symptoms following fracture-related infection: a systematic review with meta-analysis of heterogeneous evidence
Johann Alexander Betker, Nike Walter, Markus Rupp, Susanne Baertl, and Volker Alt
J. Bone Joint Infect., 11, 569–577, https://doi.org/10.5194/jbji-11-569-2026,https://doi.org/10.5194/jbji-11-569-2026, 2026
Short summary
Sonication versus peri-implant tissue culture in fracture-related infection: diagnostic performance and therapeutic consequences in a single-center cohort
Belal Abdo, Daniel Strack, Marcel Schäuffele, Tim Ludwig Tüngler, Can Imirzalioglu, Anita Windhorst, Moritz Fritzenwanker, Christian Heiss, and Markus Rupp
J. Bone Joint Infect., 11, 555–563, https://doi.org/10.5194/jbji-11-555-2026,https://doi.org/10.5194/jbji-11-555-2026, 2026
Short summary
Socioeconomic burden of septic re-revision surgeries for periprosthetic joint infections in Europe – a comprehensive analysis of re-revision costs
Dominik Szymski, Susanne Baertl, Nike Walter, Markus Rupp, Katja Hierl, and Volker Alt
J. Bone Joint Infect., 11, 523–533, https://doi.org/10.5194/jbji-11-523-2026,https://doi.org/10.5194/jbji-11-523-2026, 2026
Short summary
Isolation policies in musculoskeletal infection care: time to move from tradition to evidence
Laura Bessems, Jolien Onsea, Marjan Wouthuyzen-Bakker, Irene K. Sigmund, Tristan Ferry, Richard Kuehl, Martin Clauss, Alex Soriano, Ricardo Sousa, Annette Schuermans, and Willem-Jan Metsemakers
J. Bone Joint Infect., 11, 489–492, https://doi.org/10.5194/jbji-11-489-2026,https://doi.org/10.5194/jbji-11-489-2026, 2026
Short summary
Sinus tract and purulence as clinical criteria for periprosthetic joint infection: diagnostic accuracy, microorganisms, and clinical outcomes
Markus Luger, Martin McNally, Lukas Rabitsch, Reinhard Windhager, Richard Lass, and Irene Katharina Sigmund
J. Bone Joint Infect., 11, 305–313, https://doi.org/10.5194/jbji-11-305-2026,https://doi.org/10.5194/jbji-11-305-2026, 2026
Short summary

Cited articles

Aboyans, V., Ricco, J. B., Bartelink, M. E. L., Björck, M., Brodmann, M., Cohnert, T., Collet, J. P., Czerny, M., De Carlo, M., Debus, S., Espinola-Klein, C., Kahan, T., Kownator, S., Mazzolai, L., Naylor, A. R., Roffi, M., Röther, J., Sprynger, M., Tendera, M., Tepe, G., Venermo, M., Vlachopoulos, C., and Desormais, I.: ESC Scientific Document Group, ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries Endorsed by: the European Stroke Organization (ESO) The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS), Eur. Heart J., 39, 763–816., https://doi.org/10.1093/eurheartj/ehx095, 2018. 
Ali, N., Hamouda, R., Tarek, R., Abdelhamid, M., Lashin, A., Hassan, R., Gamal, R., Elfaham, M., Attia, A., Abdelaleem, A., Sakna, N., Gamal, A., Aboelenin, S., AbdelHafez, R., Abdelkader, S., and Nabhan, A.: Non-adherence to surgical antibiotic prophylaxis guidelines: findings from a mixed-methods study in a developing country, Antimicrob. Resist. Infect. Control, 14, 89, https://doi.org/10.1186/s13756-025-01607-5, 2025. 
Alt, V., McNally, M., Wouthuyzen-Bakker, M., Metsemakers, W. J., Marais, L., Zalavras, C., and Morgenstern, M.: The FRI classification – A new classification of fracture-related infections, Injury, 55, 111831, https://doi.org/10.1016/j.injury.2024.111831, 2024. 
Short summary
This article outlines 20 common errors in the prevention, diagnosis, and management of fracture-related infection (FRI), highlighting their clinical consequences and providing practical recommendations for avoiding them. By addressing typical pitfalls and emphasizing standardized procedures and interdisciplinary collaboration, the article aims to improve patient safety and treatment outcomes.
Share