Articles | Volume 10, issue 6
https://doi.org/10.5194/jbji-10-581-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-581-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Original full-length article
| 
09 Dec 2025
Original full-length article |
| 09 Dec 2025
| 09 Dec 2025
Evaluation of bacterial adherence and biofilm development on an anodized stainless-steel surface for the prevention of osteosynthesis-associated infections
Marina Medel-Plaza
Department of Clinical Microbiology. IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain
María Angeles Arenas
CIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
National Centre of Metallurgical Research, CENIM-CSIC, Madrid, Spain
John J. Aguilera-Correa
Department of Clinical Microbiology. IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain
CIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
Amber De Bleeckere
Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium
Aranzazu Mediero
Joint and Bone Research Unit, IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain
Ignacio García
National Centre of Metallurgical Research, CENIM-CSIC, Madrid, Spain
Juan J. De Damborenea
CIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
National Centre of Metallurgical Research, CENIM-CSIC, Madrid, Spain
Jaime Esteban
Department of Clinical Microbiology. IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain
CIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
Tom Coenye
Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium
CIBERINFEC-CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain
National Centre of Metallurgical Research, CENIM-CSIC, Madrid, Spain
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J. Bone Joint Infect., 9, 87–97, https://doi.org/10.5194/jbji-9-87-2024, https://doi.org/10.5194/jbji-9-87-2024, 2024
Short summary
Short summary
This study conducted in multiple sites across Europe aimed to evaluate the BIOFIRE Joint Infection (JI) Panel, a new technology that uses multiplex PCR to detect microorganisms in synovial fluid of patients with suspicion of joint infections in 1 h, in comparison with synovial fluid culture. Results showed an overall agreement of 85 % to 88.4 % between the two methods. The JI Panel detected additional organisms, and the positive user experience highlights its clinical significance.
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Short summary
We have developed and evaluated an anodized stainless-steel surface treatment that significantly reduced bacterial adherence and biofilm formation by pathogens linked to orthopedic implant infections. Using laboratory conditions that mimic the human joint environment, our findings suggest that this surface treatment could enhance implant safety by preventing infection-related complications.
We have developed and evaluated an anodized stainless-steel surface treatment that significantly...
