Articles | Volume 10, issue 6
https://doi.org/10.5194/jbji-10-561-2025
https://doi.org/10.5194/jbji-10-561-2025
Original full-length article
 | 
09 Dec 2025
Original full-length article |  | 09 Dec 2025

Effect of novel antimicrobial blue light-emitting optical fiber on vancomycin-resistant Enterococcus faecium and carbapenemase-producing Klebsiella pneumoniae

Megan H. Goh, Barbara Körber-Irrgang, Lucy L. Hederick, Robert A. Rabiner, Hilmar Wisplinghoff, Antonia F. Chen, Nathalie Jazmati, and Santiago A. Lozano-Calderon

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Cited articles

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Bassetti, M., Righi, E., Carnelutti, A., Graziano, E., and Russo, A.: Multidrug-resistant Klebsiella pneumoniae: challenges for treatment, prevention and infection control, Expert Rev. Anti-Infect. Ther., 16, 749–761, https://doi.org/10.1080/14787210.2018.1522249, 2018. 
Bauer, R., Hoenes, K., Meurle, T., Hessling, M., and Spellerberg, B.: The effects of violet and blue light irradiation on ESKAPE pathogens and human cells in presence of cell culture media, Sci. Rep., 11, 24473, https://doi.org/10.1038/s41598-021-04202-x, 2021. 
Bravo, A. R., Fuentealba, F. A., González, I. A., and Palavecino, C. E.: Use of Antimicrobial Photodynamic Therapy to Inactivate Multidrug-Resistant Klebsiella pneumoniae: Scoping Review, Pharmaceutics, 16, 1626, https://doi.org/10.3390/pharmaceutics16121626, 2024. 
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Short summary
This study explored whether blue light could help treat difficult joint implant infections caused by drug-resistant bacteria. A new optical fiber that delivers light evenly was tested in the lab. Blue light reduced bacteria more with higher power and longer exposure. These findings suggest that this fiber could support future light-based treatments for deep surgical infections.
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