Journal of Bone and Joint Infection
Journal of Bone and Joint Infection
JBJI
Articles | Volume 10, issue 6
Articles | Volume 10, issue 6
https://doi.org/10.5194/jbji-10-425-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/jbji-10-425-2025
© Author(s) 2025. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 10, issue 6
Review
 | 
05 Nov 2025
Review |  | 05 Nov 2025

Infective endocarditis meets native vertebral osteomyelitis: a mortality perspective

Fabio Borgonovo, Francesco Petri, Takahiro Matsuo, Rita Igwilo-Alaneme, Mohammad Seyed Amin Alavi, Omar K. Mahmoud, Said El Zein, Matteo Passerini, Mohammad Hassan Murad, Daniel C. DeSimone, Ahmad Nassr, Aaron J. Tande, Andrea Gori, and Elie F. Berbari

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Short summary
We studied a serious double infection affecting the heart and spine, often seen in older or immunocompromised patients. By analyzing systematic data from the literature, we found that this condition leads to high death rates, especially when caused by the bacterium Staphylococcus aureus. Our work highlights the urgent need for higher-quality studies and better coordinated care. These findings may help guide future treatment strategies and improve outcomes for affected patients.
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