Same Organism, Different Phenotype - Are Phenotypic Criteria Adequate In Coagulase-Negative Staphylococcal Orthopaedic Implant-Associated Infections?
- 1Department of Infectious Diseases, Karlstad, and Centre for Clinical Research, County Council of Värmland, Sweden
- 2School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
- 3Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark
- 4Department of Infectious Diseases and Department of Clinical and Experimental Medicine, Linköping University, Norrköping, Sweden
Abstract. In current diagnostic criteria for implant-associated bone- and joint infections, phenotypically identical low-virulence bacteria in two intraoperative cultures are usually required. Using whole-genome sequencing, we have further characterized three phenotypically different Staphylococcus capitis isolated from one prosthetic joint infection, highlighting the challenges in defining microbiological criteria for low-virulence prosthetic joint infections.