Articles | Volume 4, issue 1
J. Bone Joint Infect., 4, 16–19, 2019
https://doi.org/10.7150/jbji.30256
J. Bone Joint Infect., 4, 16–19, 2019
https://doi.org/10.7150/jbji.30256

Brief report 01 Jan 2019

Brief report | 01 Jan 2019

Same Organism, Different Phenotype - Are Phenotypic Criteria Adequate In Coagulase-Negative Staphylococcal Orthopaedic Implant-Associated Infections?

Staffan Tevell1,2, Sharmin Baig3, Åsa Nilsdotter-Augustinsson4, Marc Stegger3, and Bo Söderquist2 Staffan Tevell et al.
  • 1Department of Infectious Diseases, Karlstad, and Centre for Clinical Research, County Council of Värmland, Sweden
  • 2School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
  • 3Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark
  • 4Department of Infectious Diseases and Department of Clinical and Experimental Medicine, Linköping University, Norrköping, Sweden

Abstract. In current diagnostic criteria for implant-associated bone- and joint infections, phenotypically identical low-virulence bacteria in two intraoperative cultures are usually required. Using whole-genome sequencing, we have further characterized three phenotypically different Staphylococcus capitis isolated from one prosthetic joint infection, highlighting the challenges in defining microbiological criteria for low-virulence prosthetic joint infections.