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Journal of Bone and Joint Infection An open-access journal of the European Bone and Joint Infection Society and the MusculoSkeletal Infection Society
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Volume 4, issue 3
J. Bone Joint Infect., 4, 115–119, 2019
https://doi.org/10.7150/jbji.34679
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
J. Bone Joint Infect., 4, 115–119, 2019
https://doi.org/10.7150/jbji.34679
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.

Case report 20 Apr 2019

Case report | 20 Apr 2019

Marjolin's Tumor Complicating Chronic Periprosthetic Infection of a Total Knee Arthroplasty

Timothy Horan1, Matthew T. Wallace2, Albert J. Aboulafia2, and Janet D. Conway3 Timothy Horan et al.
  • 1Philadelphia College of Osteopathic Medicine Orthopaedic Surgery, Philadelphia, PA
  • 2MedStar Georgetown Cancer Institute, National Center for Bone and Soft Tissue Tumors, MedStar Franklin Square Medical Center
  • 3Rubin Institute for Advanced Orthopaedics, Baltimore, MD

Abstract. Marjolin's tumor is a term used to describe a malignancy developing in the setting of a chronic wound, infection, or other tissue subject to chronic inflammatory changes. These malignancies usually present after many years of chronicity, and can range from lower grade basal cell carcinomas to high-grade sarcomas. We present the case of a squamous cell carcinoma that developed within a chronic periprosthetic infection of a total knee arthroplasty of 7 years duration. The intra-articular location, association with an orthopaedic implant, and brief latency period are all unique features of this case.

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