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  <front>
    <journal-meta><journal-id journal-id-type="publisher">JBJI</journal-id><journal-title-group>
    <journal-title>Journal of Bone and Joint Infection</journal-title>
    <abbrev-journal-title abbrev-type="publisher">JBJI</abbrev-journal-title><abbrev-journal-title abbrev-type="nlm-ta">J. Bone Joint Infect.</abbrev-journal-title>
  </journal-title-group><issn pub-type="epub">2206-3552</issn><publisher>
    <publisher-name>Copernicus Publications</publisher-name>
    <publisher-loc>Göttingen, Germany</publisher-loc>
  </publisher></journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.5194/jbji-7-33-2022</article-id><title-group><article-title>Black pus from a worn-out elbow arthroplasty</article-title><alt-title>Black pus from a worn-out elbow arthroplasty</alt-title>
      </title-group><?xmltex \runningtitle{Black pus from a worn-out elbow arthroplasty}?><?xmltex \runningauthor{M. Wouthuyzen-Bakker and A. L. Boerboom}?>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes" rid="aff1">
          <name><surname>Wouthuyzen-Bakker</surname><given-names>Marjan</given-names></name>
          <email>m.wouthuyzen-bakker@umcg.nl</email>
        <ext-link>https://orcid.org/0000-0001-7866-2467</ext-link></contrib>
        <contrib contrib-type="author" corresp="no" rid="aff2">
          <name><surname>Boerboom</surname><given-names>Alexander L.</given-names></name>
          
        </contrib>
        <aff id="aff1"><label>1</label><institution>Department of Medical Microbiology and Infection Prevention, University of
Groningen,<?xmltex \hack{\break}?> University Medical Center Groningen, Groningen, the Netherlands​​​​​​​</institution>
        </aff>
        <aff id="aff2"><label>2</label><institution>Department of Orthopaedic Surgery, University of Groningen, University
Medical Center Groningen, Groningen, the Netherlands</institution>
        </aff>
      </contrib-group>
      <author-notes><corresp id="corr1">Marjan Wouthuyzen-Bakker (m.wouthuyzen-bakker@umcg.nl)</corresp></author-notes><pub-date><day>7</day><month>February</month><year>2022</year></pub-date>
      
      <volume>7</volume>
      <issue>1</issue>
      <fpage>33</fpage><lpage>34</lpage>
      <history>
        <date date-type="received"><day>19</day><month>December</month><year>2021</year></date>
           <date date-type="rev-recd"><day>23</day><month>January</month><year>2022</year></date>
           <date date-type="accepted"><day>24</day><month>January</month><year>2022</year></date>
      </history>
      <permissions>
        <copyright-statement>Copyright: © 2022 Marjan Wouthuyzen-Bakker</copyright-statement>
        <copyright-year>2022</copyright-year>
      <license license-type="open-access"><license-p>This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link></license-p></license></permissions><self-uri xlink:href="https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022.html">This article is available from https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022.html</self-uri><self-uri xlink:href="https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022.pdf">The full text article is available as a PDF file from https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022.pdf</self-uri>
    </article-meta>
  </front>
<body>
      

<sec id="Ch1.S1" sec-type="intro">
  <label>1</label><title>Clinical picture</title>
      <p id="d1e102">A 64-year-old woman with a medical history of rheumatoid arthritis and
multiple joint prostheses presented to our hospital. She had been experiencing pain
and a greyish swelling in her left elbow, which had undergone arthroplasty 25 years prior. The swelling eventually opened and drained black metal-like pus
(Fig. 1). The prosthesis (a Kudo type 15) was extracted in a two-stage
exchange procedure in which dark-grey debris and necrosis were observed
(Fig. 2). Cultures revealed the presence of a polymicrobial periprosthetic
joint infection (PJI). The patient was treated with amoxicillin and clavulanic acid for 6 weeks and had a flail elbow for 1 year. Finally she received
a successful revision arthroplasty with a Coonrad-Morrey elbow prosthesis.</p>

      <?xmltex \floatpos{h!}?><fig id="Ch1.F1"><?xmltex \currentcnt{1}?><?xmltex \def\figurename{Figure}?><label>Figure 1</label><caption><p id="d1e107">Draining sinus with black pus.</p></caption>
        <?xmltex \igopts{width=236.157874pt}?><graphic xlink:href="https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022-f01.jpg"/>

      </fig>

      <?xmltex \floatpos{t}?><fig id="Ch1.F2"><?xmltex \currentcnt{2}?><?xmltex \def\figurename{Figure}?><label>Figure 2</label><caption><p id="d1e118">Grey-coloured synovitis and necrosis caused by metallic wear
debris due to the release of cobalt, chromium, and titanium particles
(Brinkman et al., 2007).</p></caption>
        <?xmltex \igopts{width=227.622047pt}?><graphic xlink:href="https://jbji.copernicus.org/articles/7/33/2022/jbji-7-33-2022-f02.jpg"/>

      </fig>

</sec>
<sec id="Ch1.S2" sec-type="conclusions">
  <label>2</label><title>Conclusion</title>
      <p id="d1e135">A worn-out elbow prosthesis causes polyethylene wear and, eventually, severe metallosis when not revised in a timely manner. Damage to the joint, surrounding bone,
and soft tissue results in an impaired local immunity and sinus to the skin.
These factors make the prosthetic joint more prone to subsequent
polymicrobial infection (Barba et al., 2015; Tai et al., 2021).</p>
</sec>

      
      </body>
    <back><notes notes-type="dataavailability"><title>Data availability</title>

      <p id="d1e142">No data sets were used in this article.</p>
  </notes><notes notes-type="authorcontribution"><title>Author contributions</title>

      <p id="d1e148">MWB and AL contributed equally in writing the text.</p>
  </notes><notes notes-type="competinginterests"><title>Competing interests</title>

      <p id="d1e154">At least one of the (co-)authors is a member of the editorial board of <italic>Journal of Bone and Joint Infection</italic>. The peer-review process was guided by an independent editor, and the authors also have no other competing interests to declare.</p>
  </notes><notes notes-type="disclaimer"><title>Disclaimer</title>

      <p id="d1e164">Publisher’s note: Copernicus Publications remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.</p>
  </notes><ack><title>Acknowledgements</title><p id="d1e170">The authors would like to thank the patient for her willingness to publish her pictures.</p></ack><notes notes-type="reviewstatement"><title>Review statement</title>

      <p id="d1e175">This paper was edited by Parham Sendi and reviewed by two anonymous referees.</p>
  </notes><?xmltex \hack{\newpage}?><ref-list>
    <title>References</title>

      <ref id="bib1.bib1"><label>1</label><?label 1?><mixed-citation>
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  </ref-list></back>
    <!--<article-title-html>Black pus from a worn-out elbow arthroplasty</article-title-html>
<abstract-html/>
<ref-html id="bib1.bib1"><label>1</label><mixed-citation>
Barba, T., Wach, J., Lustig, S., Laurent, F., Devouassoux-Shisheboran, M., Valour, F.,   Chidiac, C.,  Ferry, T., and Lyon BJI Study Group​​​​​​​: Metallosis-associated prosthetic joint infection, Med. Mal. Infect.,
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<ref-html id="bib1.bib2"><label>2</label><mixed-citation>
Brinkman, J. M., de Vos, M. J., and Eygendaal, D.: Failure mechanisms in uncemented Kudo
type 5 elbow prosthesis in patients with rheumatoid arthritis, Acta
Orthop.,  78, 263–270, 2007.
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<ref-html id="bib1.bib3"><label>3</label><mixed-citation>
Tai, D. B. G., Patel, R., Abdel, M. P., Berbari, E. F., and Tande, A. J.: Microbiology of hip and
knee periprosthetic joint infections: a database study, Clin. Microbiol.
Infect., 28, P255–259, <a href="https://doi.org/10.1016/j.cmi.2021.06.006" target="_blank">https://doi.org/10.1016/j.cmi.2021.06.006</a>​​​​​​​, 2021.
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