JBJI Journal of Bone and Joint Infection JBJI J. Bone Joint Infect. 2206-3552 Ivyspring Göttingen, Germany 10.7150/jbji.24366 Results and Patient Reported Outcome Measures (PROMs) after One-Stage Revision for Periprosthetic Joint Infection of the Hip: A Single-centre Retrospective Study Kuiper Jesse W.P. 1 2 Rustenburg Christine M.E. 1 Willems Jore H. 2 3 Verberne Steven J. 2 Peters Edgar J.G. 4 5 Saouti Rachid 1 Department of Orthopaedic Surgery, VU University Medical Centre, Amsterdam, the Netherlands Department of Orthopaedic Surgery, Noord-West Ziekenhuisgroep, Alkmaar, the Netherlands Department of Orthopaedic Surgery, Spaarne Gasthuis, Hoofddorp, the Netherlands Department of Internal Medicine, VU University Medical Centre, Amsterdam, the Netherlands Amsterdam Infection and Immunity Institute, Amsterdam, the Netherlands 06 07 2018 3 3 143 149 Copyright: © 2018 Jesse W.P. Kuiper et al. 2018 This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/ This article is available from https://jbji.copernicus.org/articles/3/143/2018/jbji-3-143-2018.html The full text article is available as a PDF file from https://jbji.copernicus.org/articles/3/143/2018/jbji-3-143-2018.pdf

<p class="p p-first" id="__p3"><strong><em>Background</em>:</strong> Little is known about functional outcome and quality of life (QoL) after one-stage revision for periprosthetic joint infection (PJI) of the hip.</p><p id="__p4"><em>Methods</em>: a cohort of 30 subjects treated with one-stage revision between 2011 and 2015 was identified, and questionnaires on functional outcome and QoL were distributed.</p><p id="__p5"><strong><em>Results</em>:</strong> 28 subjects were successfully treated (93%). Most subjects were referred from other hospitals. Coagulase-negative<em> Staphylococcus</em> was found in 50% of the cases, and 40% of all cultured bacteria were multidrug-resistant. 25% had subsequent revision surgery, unrelated to PJI. Functional outcome was good and QoL scores were high, comparable to prosthetic joint revision surgery in general.</p><p class="p p-last" id="__p6"><strong><em>Conclusion</em>:</strong> Although the cohort was small and statistical analysis was not performed, this study showed that excellent results can be obtained with one-stage revision for hip PJI. Functional outcome and QoL was comparable to prosthetic joint revision surgery in general.</p>

 References Bozic KJ, Ries MD. The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization. J Bone Joint Surg Am. 2005;87:1746–51. Osmon DR, Berbari EF, Berendt AR, Lew D, Zimmerli W, Steckelberg JM. et al. Diagnosis and management of prosthetic joint infection: Clinical practice guidelines by the infectious Diseases Society of America. Clin Infect Dis. 2013;56:1–25. Leonard HAC, Liddle AD, Burke O, Murray DW, Pandit H. Single- or two-stage revision for infected total hip arthroplasty? A systematic review of the literature. Clin Orthop Relat Res. 2014;472:1036–42. [PMC free article] Nguyen M, Sukeik M, Zahar A, Nizam I, Haddad FS. One-stage Exchange Arthroplasty for Periprosthetic Hip and Knee Joint Infections. Open Orthop J. 2016;10:646–53. [PMC free article] Oussedik SIS, Dodd MB, Haddad FS. Outcomes of revision total hip replacement for infection after grading according to a standard protocol. J Bone Joint Surg Br. 2010;92:1222–6. Rietbergen L, Kuiper JWP, Walgrave S, Hak L, Colen S. Quality of life after staged revision for infected total hip arthroplasty: A systematic review. Hip Int. 2016;26:311–8. Strange S, Whitehouse MR, Beswick AD, Board T, Burston A, Burston B. et al. One-stage or two-stage revision surgery for prosthetic hip joint infection - the INFORM trial: a study protocol for a randomised controlled trial. Trials. 2016;17:90. [PMC free article] Zmistowski B, Della Valle C, Bauer TW, Malizos KN. Diagnosis of Periprosthetic Joint Infection. J Orthop Res. 2014;32:S98–107. Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG. et al. Bacteria : an International Expert Proposal for interim standard definitions for acquired resistance. Microbiology. 2011;18:268–81. Nederlandse Orthopaedische Vereniging (NOV) Patient Reported Outcome Measures. 2012. Gosens T, Hoefnagels NHM, de Vet RCW, Dhert WJA, van Langelaan EJ, Bulstra SK. et al. The “Oxford Heup Score” Acta Orthop. 2005;76:204–11. de Groot IB, Reijman M, Terwee CB, Bierma-Zeinstra SMA, Favejee M, Roos EM. et al. Validation of the Dutch version of the Hip disability and Osteoarthritis Outcome Score. Osteoarthr Cartil. 2007;15:104–9. Lamers LM, McDonnell J, Stalmeier PFM, Krabbe PFM, Busschbach JJ V. The Dutch tariff: Results and arguments for an effective design for national EQ-5D valuation studies. Health Econ. 2006;15:1121–32. Winkler H, Stoiber a, Kaudela K, Winter F, Menschik F. One stage uncemented revision of infected total hip replacement using cancellous allograft bone impregnated with antibiotics. J Bone Joint Surg Br. 2008;90:1580–4. Loty B, Postel M, Evrard J, Courpied JP. Remplacements en un temps des protheses totales de hanches infectees et reconstructions osseuses par allogreffes. Int Orthop. 1992;16:330–8. van Diemen MPJ, Colen S, Dalemans AAR, Stuyck J, Mulier M. Two-stage revision of an infected total hip arthroplasty: A follow-up of 136 patients. Hip Int. 2013;23:445–50. Mahmoud AN, Sundberg M, Flivik G. Comparable results with porous metal augments in combination with either cemented or uncemented cups in revision hip arthroplasty: an analysis of one hundred forty-seven revisions at a mean of five years. J Arthroplasty. 2017;32:1612–7. Jenny J-Y, Lengert R, Diesinger Y, Gaudias J, Boeri C, Kempf J-F. Routine one-stage exchange for chronic infection after total hip replacement. Int Orthop. 2014;38:2477–81. Grammatopoulos G, Kendrick B, McNally M, Athanasou NA, Atkins B, McLardy-Smith P. et al. Outcome following Debridement, Antibiotics, and Implant Retention in hip Periprosthetic Joint Infection—An 18-Year Experience. J Arthroplasty. 2017;32:2248–55. Philpott A, Weston-Simons JS, Grammatopoulos G, Bejon P, Gill HS, McLardy-Smith P. et al. Predictive outcomes of revision total hip replacement - A consecutive series of 1176 patients with a minimum 10-year follow-up. Maturitas. 2014;77:185–90. Hoberg M, Konrads C, Engelien J, Oschmann D, Holder M, Walcher M. et al. Similar outcomes between two-stage revisions for infection and aseptic hip revisions. Int Orthop. 2016;40:459–64. Choi HR, Kwon YM, Freiberg AA, Malchau H. Comparison of one-stage revision with antibiotic cement versus two-stage revision results for infected total hip arthroplasty. J Arthroplasty. 2013;28:66–70. Klouche S, Leonard P, Zeller V, Lhotellier L, Graff W, Leclerc P. et al. Infected total hip arthroplasty revision: One- or two-stage procedure? Orthop Traumatol Surg Res. 2012;98:144–50. De Man FHR, Sendi P, Zimmerli W, Maurer TB, Ochsner PE, Ilchmann T. Infectiological, functional, and radiographic outcome after revision for prosthetic hip infection according to a strict algorithm. Acta Orthop. 2011;82:27–34. [PMC free article] Scharfenberger A, Clark M, Lavoie G, Connor GO, Beaupre LA. Treatment of an infected total hip replacement with the PROSTALAC system. Part 2 : Health-related quality of life and function with the PROSTALAC implant in situ. Can J Surg. 2007;50:29–33. [PMC free article] Raman R, Kamath RP, Parikh A, Angus PD. Revision of cemented hip arthroplasty using a hydroxyapatite-ceramic-coated femoral component. J Bone Joint Surg Br. 2005;87:1061–7. Dawson J, Fitzpatrick R, Frost S, Gundle R, McLardy-Smith P, Murray D. Evidence for the validity of a patient-based instrument for assessment of outcome after revision hip replacement. J Bone Joint Surg Br. 2001;83B:1125–9.